HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 946488Generated: October 31, 2026
Trifluoroacetic acid → N-(2-Fluoro-4-{[2-({[3-(hydroxymethyl)azetidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
https://huagongshe.com/reaction/946488
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | (Azetidin-3-yl)methanol | HCID 13400658 | — |
| Reactant | N-(4-(2-aminopyridin-4-yloxy)-2-fluorophenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | HCID 59596943 | — |
| Product | N-(2-Fluoro-4-{[2-({[3-(hydroxymethyl)azetidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide | HCID 16118809 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-91346d779acb4e6c93cf383df824c0fb |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
