Acetonitrile → 7-Benzyl-N-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine

HRID 94651Notes

Reaction equation

HRID 94651 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[n:11][cH:12][n:13][c:14]([Cl:18])[c:15]2[CH2:16][CH2:17]1.[CH3:27][C:28]#[N:29].[F:19][c:20]1[cH:21][cH:22][c:23]([NH2:26])[cH:24][cH:25]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[n:11][cH:12][n:13][c:14]([NH:26][c:23]3[cH:22][cH:21][c:20]([F:19])[cH:25][cH:24]3)[c:15]2[CH2:16][CH2:17]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 97314-FluoroanilineHCID 219588387-Benzyl-4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine

Product 1

HCID 597717947-Benzyl-N-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-bddda7d454994c4fa6d8efb4d668445e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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