Dichloromethane → tert-butyl N-[4-[[1-cyano-2-(4-iodophenyl)ethyl]carbamoyl]oxan-4-yl]carbamate

HRID 946522Notes

Reaction equation

HRID 946522 reaction equation
[Cl:30][CH2:31][Cl:32].[NH2:1][C:2]([CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[C:15]1([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1)=[O:29]>>[N:1]#[C:2][CH:3]([CH2:4][c:5]1[cH:6][cH:7][c:8]([I:11])[cH:9][cH:10]1)[NH:12][C:13](=[O:14])[C:15]1([NH:21][C:22]([O:23][C:24]([CH3:25])([CH3:26])[CH3:27])=[O:28])[CH2:16][CH2:17][O:18][CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 68431026tert-butyl N-[4-[[1-amino-3-(4-iodophenyl)-1-oxopropan-2-yl]carbamoyl]oxan-4-yl]carbamate

Product 1

HCID 68430038tert-butyl N-[4-[[1-cyano-2-(4-iodophenyl)ethyl]carbamoyl]oxan-4-yl]carbamate

Sources & evidence

ORD record
ord-7dea971e03dc4be6b3422540c7dac9e7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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