3-(4-Methylpiperazin-1-yl)aniline → N(8)-(3-Methoxy-benzyl)-N(2)-[3-(4-methyl-piperazin-1-yl)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

HRID 946542Notes

Reaction equation

HRID 946542 reaction equation
[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][c:10]([NH2:11])[cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1.[Cl:15][c:16]1[n:17][n:18]2[c:19]([c:20]([NH:24][CH2:25][c:26]3[cH:27][c:28]([O:32][CH3:33])[cH:29][cH:30][cH:31]3)[cH:21][cH:22][cH:23]2)[n:34]1>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([c:8]2[cH:9][c:10]([NH:11][c:16]3[n:17][n:18]4[c:19]([c:20]([NH:24][CH2:25][c:26]5[cH:27][c:28]([O:32][CH3:33])[cH:29][cH:30][cH:31]5)[cH:21][cH:22][cH:23]4)[n:34]3)[cH:12][cH:13][cH:14]2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 115646133-(4-Methylpiperazin-1-yl)anilineHCID 67481427(2-Chloro-[1,2,4]triazolo[1,5-a]pyridin-8-yl)-(3-methoxy-benzyl)-amine

Product 1

HCID 59612435N(8)-(3-Methoxy-benzyl)-N(2)-[3-(4-methyl-piperazin-1-yl)-phenyl]-[1,2,4]triazolo[1,5-a]pyridine-2,8-diamine

Sources & evidence

ORD record
ord-45ffb93651844cb894dd1d239cb13155
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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