1-(Ethanesulfonyl)piperazine → 3-amino-6-(4-(ethylsulfonyl)piperazin-1-yl)-N-phenylpyrazine-2-carboxamide
Reaction equation
[CH2:18]([CH3:19])[S:20](=[O:21])(=[O:22])[N:23]1[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]1.[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[n:4][c:5]([Br:8])[cH:6][n:7]1>>[NH2:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[n:4][c:5]([N:26]2[CH2:25][CH2:24][N:23]([S:20]([CH2:18][CH3:19])(=[O:21])=[O:22])[CH2:28][CH2:27]2)[cH:6][n:7]1Participants
3
Sources & evidence
- ORD record
- ord-fda4a05cec7948fb8f2ab19bd7dee42d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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