Cyclohexanone → N-(1-Cyclohexyl-piperidin-4-yl)-N-(4-fluoro-phenyl)-acetamide
Reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]([C:9]([CH3:10])=[O:11])[CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:6][cH:7]1.[O:18]=[C:19]1[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([N:8]([C:9]([CH3:10])=[O:11])[CH:12]2[CH2:13][CH2:14][N:15]([CH:19]3[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]3)[CH2:16][CH2:17]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-5f10f9628079419494a88d855f4ef75d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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