tert-butyl 2-(tert-butylcarbamoyl)-4-hydroxypyrrolidine-1-carboxylate → benzyl N-[4-amino-1-[[4-[2-(tert-butylcarbamoyl)-4-hydroxypyrrolidin-1-yl]-3-hydroxy-4-oxo-1-phenylbutan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamate
Reaction equation
[C:33]([O:34][C:35](=[O:36])[N:40]1[CH:41]([C:42](=[O:43])[NH:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:49][CH:50]([OH:52])[CH2:51]1)([CH3:37])([CH3:38])[CH3:39].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([CH2:13][C:14]([NH2:15])=[O:16])[C:17](=[O:18])[NH:19][CH:20]([CH:21]([C:22](=[O:23])[OH:24])[OH:25])[CH2:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]([CH2:13][C:14]([NH2:15])=[O:16])[C:17](=[O:18])[NH:19][CH:20]([CH:21]([C:22](=[O:24])[N:40]1[CH:41]([C:42](=[O:43])[NH:44][C:45]([CH3:46])([CH3:47])[CH3:48])[CH2:49][CH:50]([OH:52])[CH2:51]1)[OH:25])[CH2:26][c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f1a131df8b2d4d29916e49abd6e6e9a8
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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