Acetate → Ethyl 3-(cyclopentylamino)-2,2-dimethylpropanoate

HRID 946750Notes

Reaction equation

HRID 946750 reaction equation
[C:22]([O:23][BH-:24]([O:25][C:26](=[O:27])[CH3:28])[O:29][C:30](=[O:31])[CH3:32])(=[O:33])[CH3:34].[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH2:6][NH2:7])([CH3:8])[CH3:9])=[O:10].[CH3:18][C:19](=[O:20])[O-:21].[Cl:36][CH2:37][Cl:38].[Na+:17].[Na+:35].[O:11]=[C:12]1[CH2:13][CH2:14][CH2:15][CH2:16]1>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH2:6][NH:7][CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16]1)([CH3:8])[CH3:9])=[O:10]

Participants

7

Reactant 6

HCID 175AcetateHCID 923Sodium ion2×HCID 6344DichloromethaneHCID 8452CyclopentanoneHCID 421529Ethyl 3-amino-2,2-dimethylpropanoateHCID 2724942Triacetoxyborohydride

Product 1

HCID 57969950Ethyl 3-(cyclopentylamino)-2,2-dimethylpropanoate

Sources & evidence

ORD record
ord-96927e483de4435e987fbdf8f60ffeb8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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