2-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-one → 5-[[1-[[2,4-Bis(trifluoromethyl)phenyl]methyl]-3-iodoindazol-5-yl]methylidene]-2-[2-(hydroxymethyl)morpholin-4-yl]-1,3-thiazol-4-one

HRID 94676Notes

Reaction equation

HRID 94676 reaction equation
[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][c:8]([I:17])[c:9]3[cH:10][c:11]([CH:15]=[O:16])[cH:12][cH:13][c:14]23)[cH:18][cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]1)([F:26])[F:27].[OH:28][CH2:29][CH:30]1[O:31][CH2:32][CH2:33][N:34]([C:36]2=[N:40][C:39](=[O:41])[CH2:38][S:37]2)[CH2:35]1>>[F:1][C:2]([c:3]1[c:4]([CH2:5][n:6]2[n:7][c:8]([I:17])[c:9]3[cH:10][c:11]([CH:15]=[C:38]4[S:37][C:36]([N:34]5[CH2:33][CH2:32][O:31][CH:30]([CH2:29][OH:28])[CH2:35]5)=[N:40][C:39]4=[O:41])[cH:12][cH:13][c:14]23)[cH:18][cH:19][c:20]([C:22]([F:23])([F:24])[F:25])[cH:21]1)([F:26])[F:27]

Participants

3

Reactant 2

HCID 672406862-(2-Hydroxymethyl-morpholin-4-yl)-thiazol-4-oneHCID 866545851-(2,4-Bis-trifluoromethyl-benzyl)-3-iodo-1H-indazole-5-carbaldehyde

Product 1

HCID 767564275-[[1-[[2,4-Bis(trifluoromethyl)phenyl]methyl]-3-iodoindazol-5-yl]methylidene]-2-[2-(hydroxymethyl)morpholin-4-yl]-1,3-thiazol-4-one

Sources & evidence

ORD record
ord-e15d5a4e77f743f98d3be6ac271c3556
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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