Dichloromethane → 4-[4-(3,4,4a,5,6,7,8,8a-octahydro-2H-quinoline-1-carbonyl)thiophen-2-yl]piperidine-1-carboxamide
Reaction equation
[CH3:24][Si:25]([CH3:26])([CH3:27])[N:28]=[C:29]=[O:30].[Cl:31][CH2:32][Cl:33].[N:1]1([C:11](=[O:12])[c:13]2[cH:14][s:15][c:16]([CH:18]3[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]3)[cH:17]2)[CH2:2][CH2:3][CH2:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:10]12>>[N:1]1([C:11](=[O:12])[c:13]2[cH:14][s:15][c:16]([CH:18]3[CH2:19][CH2:20][N:21]([C:29]([NH2:28])=[O:30])[CH2:22][CH2:23]3)[cH:17]2)[CH2:2][CH2:3][CH2:4][CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:10]12Participants
4
Sources & evidence
- ORD record
- ord-28dba35a4b5a42b6b2157baac6358188
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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