Acetic Acid → Ethyl 5-amino-6,7-difluoro-1,4-dihydro-4-oxo-1-(tetrahydropyran-4-yl)-3-quinolinecarboxylate
Reaction equation
[C:33]([OH:34])(=[O:35])[CH3:36].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][c:9]1[c:10]2[c:11](=[O:32])[c:12]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:13][n:14]([CH:21]3[CH2:22][CH2:23][O:24][CH2:25][CH2:26]3)[c:15]2[cH:16][c:17]([F:20])[c:18]1[F:19]>>[NH2:8][c:9]1[c:10]2[c:11](=[O:32])[c:12]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:13][n:14]([CH:21]3[CH2:22][CH2:23][O:24][CH2:25][CH2:26]3)[c:15]2[cH:16][c:17]([F:20])[c:18]1[F:19]Participants
3
Sources & evidence
- ORD record
- ord-3f76ecb09d3c47039d6e72879b7bd518
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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