Dichloromethane → 4-(3-Fluoro-2-methylpropyl)-1-(1-phenylethyl)pyrrolidin-2-one
Reaction equation
[CH2:1]([N:2]([S:3]([F:4])([F:5])[F:7])[CH2:6][CH3:8])[CH3:9].[Cl:29][CH2:30][Cl:31].[OH:10][CH2:11][CH:12]([CH2:13][CH:14]1[CH2:15][C:16](=[O:27])[N:17]([CH:19]([CH3:20])[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:18]1)[CH3:28]>>[F:7][CH2:11][CH:12]([CH2:13][CH:14]1[CH2:15][C:16](=[O:27])[N:17]([CH:19]([CH3:20])[c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:18]1)[CH3:28]Participants
4
Sources & evidence
- ORD record
- ord-a5af6999dad54d6bb20c3302bf266786
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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