1-[(Pyrrolidin-2-yl)methyl]piperidine → 2-Fluoro-5-[3-oxo-3-[2-(piperidin-1-ylmethyl)pyrrolidin-1-yl]prop-1-enyl]benzonitrile
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([CH:10]=[CH:11][C:12](=[O:13])[OH:14])[cH:6][cH:7][c:8]1[F:9].[NH:15]1[CH:16]([CH2:20][N:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[CH2:17][CH2:18][CH2:19]1>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([CH:10]=[CH:11][C:12](=[O:14])[N:15]2[CH:16]([CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[CH2:17][CH2:18][CH2:19]2)[cH:6][cH:7][c:8]1[F:9]Participants
3
Sources & evidence
- ORD record
- ord-b46184d8825f45ec91fd716cdf030e2d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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