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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 947103Generated: November 1, 2026

Benzene → 2-Fluoro-3-(hydroxymethyl)pyridine

https://huagongshe.com/reaction/947103

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneHCID 241—
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantThionyl ChlorideHCID 24386—
ReactantBorohydrideHCID 28123—
Reactant1,4-DioxaneHCID 31275—
Reactant2-Fluoronicotinic acidHCID 96089—
Product2-Fluoro-3-(hydroxymethyl)pyridineHCID 14761461—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-7f3ca452d9474a8daf9cb3c4d6fd3dac
Source noteValidation data from https://doi.org/10.1039/C8SC04228D