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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 947139Generated: November 4, 2026

2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-{5-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-thiophen-2-yl}-pyrimidin-2-ylamine

https://huagongshe.com/reaction/947139

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Aminopyrimidine-5-boronic acid, pinacol esterHCID 17750212—
Reactant2-(5-Bromo-thiophen-2-yl)-6-methyl-4-(4-trifluoromethyl-phenyl)-pyridineHCID 57468800—
Product5-{5-[6-Methyl-4-(4-trifluoromethyl-phenyl)-pyridin-2-yl]-thiophen-2-yl}-pyrimidin-2-ylamineHCID 24760511—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5cea5e6552c5441fac7206289f869dfa
Source noteValidation data from https://doi.org/10.1039/C8SC04228D