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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 947250Generated: October 26, 2026

Hydrochloric Acid → Tert-butyl 3-[[7-[2-(4-methylpiperazin-1-yl)ethoxy]naphthalen-2-yl]methoxy]-4-[4-(3-phenylmethoxypropoxy)phenyl]piperidine-1-carboxylate

https://huagongshe.com/reaction/947250

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantIodide IonHCID 30165—
ReactantHydrideHCID 166653—
Reactant1-(2-Chloroethyl)-4-methylpiperazineHCID 413791—
Reactanttert-butyl (3RS,4RS)-4-[4-(3-benzyloxy-propoxy)-phenyl]-3-(7-hydroxy-naphthalen-2-ylmethoxy)-piperidine-1-carboxylateHCID 57256197—
ProductTert-butyl 3-[[7-[2-(4-methylpiperazin-1-yl)ethoxy]naphthalen-2-yl]methoxy]-4-[4-(3-phenylmethoxypropoxy)phenyl]piperidine-1-carboxylateHCID 53909120—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-71d3185c89fc40289c4d1e565f088bef
Source noteValidation data from https://doi.org/10.1039/C8SC04228D