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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 947280Generated: October 31, 2026

Ammonium → Methyl 2-chloro-5-cyclopentyl-7-[4-(difluoromethyl)-3-fluorophenyl]-5-hydroxy-3-oxoheptanoate

https://huagongshe.com/reaction/947280

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantMethyl 2-chloroacetoacetateHCID 107332—
ReactantHydrideHCID 166653—
ReactantHCID 58762224HCID 58762224—
ReactantButyllithiumHCID 178418339—
ProductMethyl 2-chloro-5-cyclopentyl-7-[4-(difluoromethyl)-3-fluorophenyl]-5-hydroxy-3-oxoheptanoateHCID 86600109—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d0d05648716b4bc19c993846155ebf54
Source noteValidation data from https://doi.org/10.1039/C8SC04228D