3-Methoxybenzyl chloride → 6-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl)-2-(3-methoxybenzyl)-2,3-dihydro-1H-isoindol-1-one
Reaction equation
[CH3:32][O:33][c:34]1[cH:35][c:36]([CH2:37][Cl:38])[cH:39][cH:40][cH:41]1.[c:1]1([CH:7]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]4[c:23]([cH:24]3)[C:22](=[O:25])[NH:21][CH2:20]4)[CH2:14][CH2:15]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][N:13]([c:16]3[cH:17][cH:18][c:19]4[c:23]([cH:24]3)[C:22](=[O:25])[N:21]([CH2:37][c:36]3[cH:35][c:34]([O:33][CH3:32])[cH:41][cH:40][cH:39]3)[CH2:20]4)[CH2:14][CH2:15]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-39739f303ccc44afa749f26d72f6044f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…