Isobutylamine → 6-(2,4-Dichloro-phenyl)-8-isobutylamino-3-morpholin-4-yl-imidazo[1,2-a]pyridine-7-carbonitrile
Reaction equation
[CH2:27]([CH:28]([CH3:29])[CH3:30])[NH2:31].[Cl:1][c:2]1[c:3]2[n:4]([cH:5][c:6](-[c:10]3[c:11]([Cl:17])[cH:12][c:13]([Cl:16])[cH:14][cH:15]3)[c:7]1[C:8]#[N:9])[c:18]([N:21]1[CH2:22][CH2:23][O:24][CH2:25][CH2:26]1)[cH:19][n:20]2.[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1>>[c:2]1([NH:31][CH2:27][CH:28]([CH3:29])[CH3:30])[c:3]2[n:4]([cH:5][c:6](-[c:10]3[c:11]([Cl:17])[cH:12][c:13]([Cl:16])[cH:14][cH:15]3)[c:7]1[C:8]#[N:9])[c:18]([N:21]1[CH2:22][CH2:23][O:24][CH2:25][CH2:26]1)[cH:19][n:20]2Participants
4
Sources & evidence
- ORD record
- ord-b6ce01401d0e4314b4c1313574538875
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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