3-Fluorobenzyl bromide → N-[6-Bromo-8-fluoro-9-(3-fluoro-benzyl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl]-isobutyramide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:10]([nH:11][c:12]2[c:13]([F:15])[cH:14]1)[CH2:9][CH2:8][CH:7]([NH:16][C:17]([CH:18]([CH3:19])[CH3:20])=[O:21])[CH2:6]3.[F:22][c:23]1[cH:24][c:25]([CH2:26][Br:27])[cH:28][cH:29][cH:30]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]3[c:10]([n:11]([CH2:26][c:25]4[cH:24][c:23]([F:22])[cH:30][cH:29][cH:28]4)[c:12]2[c:13]([F:15])[cH:14]1)[CH2:9][CH2:8][CH:7]([NH:16][C:17]([CH:18]([CH3:19])[CH3:20])=[O:21])[CH2:6]3Participants
3
Sources & evidence
- ORD record
- ord-afd37f0f0e0442fcb092ae3f1019bf24
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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