Ethanol → 4-(2-Aminopyrimidin-5-yl)-2,3-difluorobenzoic acid

HRID 947549Notes

Reaction equation

[Br:15][c:16]1[cH:17][n:18][c:19]([NH2:22])[n:20][cH:21]1.[C:23](=[O:24])([O-:25])[O-:26].[CH3:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1.[CH3:36][CH2:37][OH:38].[K+:27].[K+:28].[OH2:39].[OH:1][B:2]([c:3]1[c:4]([F:13])[c:5]([F:12])[c:6]([C:7](=[O:8])[OH:9])[cH:10][cH:11]1)[OH:14].[cH:40]1[cH:41][cH:42][c:43]([P:44]([Pd:45]([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[P:84]([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)([c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)[c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[cH:115][cH:116]1>>[c:3]1(-[c:16]2[cH:17][n:18][c:19]([NH2:22])[n:20][cH:21]2)[c:4]([F:13])[c:5]([F:12])[c:6]([C:7](=[O:8])[OH:9])[cH:10][cH:11]1