Potassium Cation → methyl 1-(4-pyridin-2-yl benzyl)-1H-indole-7-carboxylate

HRID 94758Notes

Reaction equation

HRID 94758 reaction equation
[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[cH:10][cH:11][c:12]([CH2:13][n:14]3[cH:15][cH:16][c:17]4[cH:18][cH:19][cH:20][c:21]([C:23](=[O:24])[O:25][CH3:26])[c:22]34)[cH:27][cH:28]2)[O:29]1.[Cl:77][Pd:78][Cl:79].[K+:49].[K+:50].[K+:51].[O:81]1[CH2:82][CH2:83][O:84][CH2:85][CH2:86]1.[OH2:80].[P:44]([O-:45])([O-:46])([O-:47])=[O:48].[c:52]1(-[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][c:63]1[P:64]([CH:65]1[CH2:66][CH2:67][CH2:68][CH2:69][CH2:70]1)[CH:71]1[CH2:72][CH2:73][CH2:74][CH2:75][CH2:76]1.[n:30]1[c:31]([O:36][S:37]([C:38]([F:39])([F:40])[F:41])(=[O:42])=[O:43])[cH:32][cH:33][cH:34][cH:35]1>>[c:9]1(-[c:31]2[n:30][cH:35][cH:34][cH:33][cH:32]2)[cH:10][cH:11][c:12]([CH2:13][n:14]2[cH:15][cH:16][c:17]3[cH:18][cH:19][cH:20][c:21]([C:23](=[O:24])[O:25][CH3:26])[c:22]23)[cH:27][cH:28]1

Participants

9

Reactant 8

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 24290Palladium ChlorideHCID 312751,4-DioxaneHCID 27342162-(Dicyclohexylphosphino)biphenylHCID 39476262-Pyridyl TrifluoromethanesulfonateHCID 58307051HCID 58307051, compound

Product 1

HCID 58306536methyl 1-(4-pyridin-2-yl benzyl)-1H-indole-7-carboxylate

Sources & evidence

ORD record
ord-877b4b3f3dc541bc9dd7611f39c84bb9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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