Pyridine → 4-(4-Hydroxy-4-phenylpiperidin-1-yl)naphthalene-1-carbonitrile
Reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([F:13])[c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]12.[OH:14][C:15]1([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[cH:27]1[cH:28][cH:29][n:30][cH:31][cH:32]1>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([N:18]2[CH2:17][CH2:16][C:15]([OH:14])([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[CH2:20][CH2:19]2)[c:7]2[cH:8][cH:9][cH:10][cH:11][c:12]12Participants
4
Sources & evidence
- ORD record
- ord-b3f8db51ec27483f9a0fde848b630d77
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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