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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 947960Generated: November 1, 2026

Acetate → 5-(2,2-Difluoro-ethoxy)-7-methyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one

https://huagongshe.com/reaction/947960

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetateHCID 175—
ReactantTolueneHCID 1140—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
ReactantAllyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 105144—
Reactant2,2-Difluoroethan-1-olHCID 136187—
ReactantHCID 11560384HCID 11560384—
Product5-(2,2-Difluoro-ethoxy)-7-methyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-oneHCID 86635675—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-43e54d1c46a04c7eae9065d5e6aa13b2
Source noteValidation data from https://doi.org/10.1039/C8SC04228D