Acetyl chloride → (3-{2-[(Acetyl-benzyl-amino)-methyl]-4-trifluoromethyl-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([O:14][c:15]2[c:16]([CH2:25][NH:26][CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[c:9]([O:12][CH3:13])[cH:10][cH:11]1)=[O:34].[CH3:35][C:36]([Cl:37])=[O:38]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8]([O:14][c:15]2[c:16]([CH2:25][N:26]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[C:36]([CH3:35])=[O:38])[cH:17][c:18]([C:21]([F:22])([F:23])[F:24])[cH:19][cH:20]2)[c:9]([O:12][CH3:13])[cH:10][cH:11]1)=[O:34]Participants
3
Sources & evidence
- ORD record
- ord-e80fbc1f63b743cb9f19c718c9c987ef
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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