3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL → 7-[(5-Bromo-2-pyrazinyl)oxy]-3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepine
Reaction equation
[Br:17][c:18]1[n:19][cH:20][c:21]([Br:24])[n:22][cH:23]1.[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([OH:16])[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1>>[CH:1]1([N:5]2[CH2:6][CH2:7][c:8]3[c:9]([cH:12][c:13]([O:16][c:21]4[cH:20][n:19][c:18]([Br:17])[cH:23][n:22]4)[cH:14][cH:15]3)[CH2:10][CH2:11]2)[CH2:2][CH2:3][CH2:4]1Participants
3
Sources & evidence
- ORD record
- ord-4093d95048e34192862b24fa7d19e361
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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