5-(4-Chloro-phenyl)-2-ethynyl-pyridine → 6-[5-(4-Chloro-phenyl)-pyridin-2-ylethynyl]-2-pyrrolidin-1-ylmethyl-1,2,3,4-tetrahydro-quinoline

HRID 94831Notes

Reaction equation

HRID 94831 reaction equation
[Cl:18][c:19]1[cH:20][cH:21][c:22](-[c:25]2[cH:26][cH:27][c:28]([C:31]#[CH:32])[n:29][cH:30]2)[cH:23][cH:24]1.[I:1][c:2]1[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][CH:7]([CH2:12][N:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1)[CH2:6][CH2:5]2>>[c:2]1([C:32]#[C:31][c:28]2[cH:27][cH:26][c:25](-[c:22]3[cH:21][cH:20][c:19]([Cl:18])[cH:24][cH:23]3)[cH:30][n:29]2)[cH:3][c:4]2[c:9]([cH:10][cH:11]1)[NH:8][CH:7]([CH2:12][N:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1)[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 690789886-Iodo-2-pyrrolidin-1-ylmethyl-1,2,3,4-tetrahydro-quinoline

Product 1

HCID 117432956-[5-(4-Chloro-phenyl)-pyridin-2-ylethynyl]-2-pyrrolidin-1-ylmethyl-1,2,3,4-tetrahydro-quinoline

Sources & evidence

ORD record
ord-01673c4d4fac42058bec0de6e28f956e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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