Acetic Acid → 3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-iodopyridin-2-amine
Reaction equation
[CH3:28][C:29]#[N:30].[CH3:31][C:32](=[O:33])[OH:34].[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[O:12][c:13]2[c:14]([NH2:19])[n:15][cH:16][cH:17][cH:18]2)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8].[I:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27]>>[Cl:1][c:2]1[c:3]([CH:10]([CH3:11])[O:12][c:13]2[c:14]([NH2:19])[n:15][cH:16][c:17]([I:20])[cH:18]2)[c:4]([Cl:9])[cH:5][cH:6][c:7]1[F:8]Participants
5
Sources & evidence
- ORD record
- ord-9c118dc581f54a77bd9b20c396e30a98
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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