Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 948511Generated: November 1, 2026

Dimethyl Sulfoxide → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[3-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-N,2-dimethylpropanamide

https://huagongshe.com/reaction/948511

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantPotassium CationHCID 813—
ReactantEthyl AcetateHCID 8857—
ReactantCarbonate IonHCID 19660—
Reactant2-(Hydroxymethyl)pyrrolidin-3-OLHCID 15607343—
Reactant2-(3,5-Bis(trifluoromethyl)phenyl)-N-(6-chloro-4-(4-fluoro-2-methylphenyl)pyrid-3-yl)-N,2-dimethylpropanamideHCID 23502784—
Product2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-[3-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl]-3-pyridinyl]-N,2-dimethylpropanamideHCID 74962721—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-29d2a911426c4c56bd7161ff9c64f4d6
Source noteValidation data from https://doi.org/10.1039/C8SC04228D