Methanol → 2-(cis-4-Hydroxycyclohexyl)-2,8-diazaspiro[4.5]decan-1-one
Reaction equation
[CH3:31][OH:32].[H:29][H:30].[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:28])[C:10]3([CH2:11][CH2:12]2)[CH2:13][CH2:14][N:15]([C:18]([O:19][CH2:20][c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)=[O:27])[CH2:16][CH2:17]3)[CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][CH:5]([N:8]2[C:9](=[O:28])[C:10]3([CH2:11][CH2:12]2)[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]3)[CH2:6][CH2:7]1Participants
4
Sources & evidence
- ORD record
- ord-64fd8aa4ee7f4b5f920a55fca93d458a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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