1-(Methylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-amine → N-{2-[2-(1-Methanesulfonyl-1,2,3,4-tetrahydro-quinolin-7-ylamino)-pyrrolo[2,1-f][1,2,4]triazin-7-yl]-phenyl}-N-methyl-methanesulfonamide

HRID 94858Notes

Reaction equation

HRID 94858 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]([c:6]1[c:7](-[c:12]2[cH:13][cH:14][c:15]3[cH:16][n:17][c:18]([O:21][S:22]([C:23]([F:24])([F:25])[F:26])(=[O:27])=[O:28])[n:19][n:20]23)[cH:8][cH:9][cH:10][cH:11]1)[CH3:29].[CH3:30][S:31](=[O:32])(=[O:33])[N:34]1[CH2:35][CH2:36][CH2:37][c:38]2[cH:39][cH:40][c:41]([NH2:44])[cH:42][c:43]21>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]([c:6]1[c:7](-[c:12]2[cH:13][cH:14][c:15]3[cH:16][n:17][c:18]([NH:44][c:41]4[cH:40][cH:39][c:38]5[c:43]([cH:42]4)[N:34]([S:31]([CH3:30])(=[O:32])=[O:33])[CH2:35][CH2:36][CH2:37]5)[n:19][n:20]23)[cH:8][cH:9][cH:10][cH:11]1)[CH3:29]

Participants

3

Reactant 2

HCID 91252911-(Methylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-amineHCID 86661681Trifluoro-methanesulfonic acid 7-[2-(methanesulfonyl-methyl-amino)-phenyl]-pyrrolo[2,1-f][1,2,4]triazin-2-yl ester

Product 1

HCID 66712115N-{2-[2-(1-Methanesulfonyl-1,2,3,4-tetrahydro-quinolin-7-ylamino)-pyrrolo[2,1-f][1,2,4]triazin-7-yl]-phenyl}-N-methyl-methanesulfonamide

Sources & evidence

ORD record
ord-6743712095b843bab7e2c08a1ee776a1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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