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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 948678Generated: October 26, 2026

Dichloromethane → 8-(4-Fluoro-phenylethynyl)-4-(3-pyridin-2-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-one

https://huagongshe.com/reaction/948678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
Reactant{4-(4-Fluoro-phenylethynyl)-2-[3-oxo-3-(3-pyridin-2-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl esterHCID 86589332—
Product8-(4-Fluoro-phenylethynyl)-4-(3-pyridin-2-yl-phenyl)-1,3-dihydro-benzo[b][1,4]diazepin-2-oneHCID 22317527—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c7ff94ca7b6f45f486e373ad951f6f45
Source noteValidation data from https://doi.org/10.1039/C8SC04228D