2-Pyrrolidone → 1-{5-Chloro-2-[4-(3,5-dimethylpyridin-2-yl)piperazine-1-carbonyl]phenyl}pyrrolidin-2-one
Reaction equation
[Br:1][c:2]1[c:3]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:24])[cH:21][c:22]3[CH3:23])[CH2:15][CH2:16]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[NH:25]1[C:26](=[O:30])[CH2:27][CH2:28][CH2:29]1>>[c:2]1([N:25]2[C:26](=[O:30])[CH2:27][CH2:28][CH2:29]2)[c:3]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:24])[cH:21][c:22]3[CH3:23])[CH2:15][CH2:16]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-130e3e02bfd34c388add0648e84ad478
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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