Sodium ion → 3-Cyano-4-hexyl-quinoline-6-carboxylic acid ethyl ester

HRID 948829Notes

Reaction equation

HRID 948829 reaction equation
[CH2:19]([CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[B:25]([OH:26])[OH:27].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:9]([Cl:18])[c:10]([C:16]#[N:17])[cH:11][n:12][c:13]2[cH:14][cH:15]1.[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][c:8]2[c:9]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[c:10]([C:16]#[N:17])[cH:11][n:12][c:13]2[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 351064Hexylboronic Acid (contains varying amounts of Anhydride)HCID 585858234-Chloro-3-cyano-6-quinolinecarboxylic acid ethyl ester

Product 1

HCID 585858293-Cyano-4-hexyl-quinoline-6-carboxylic acid ethyl ester

Sources & evidence

ORD record
ord-bcc837eb6f1d4f97a8a7cb46b872b2d8
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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