Dimethyl Sulfoxide → 2-(5-Bromothiophen-2-yl)-2-[(4-chlorophenoxy)methyl]oxirane
Reaction equation
[CH3:25][S:26](=[O:27])[CH3:28].[CH3:4][S+:5]([CH3:6])[CH3:7].[Cl:8][c:9]1[cH:10][cH:11][c:12]([O:13][CH2:14][C:15](=[O:16])[c:17]2[cH:18][cH:19][c:20]([Br:22])[s:21]2)[cH:23][cH:24]1.[H-:1].[I-:3].[Na+:2]>>[CH2:4]1[C:15]([CH2:14][O:13][c:12]2[cH:11][cH:10][c:9]([Cl:8])[cH:24][cH:23]2)([c:17]2[cH:18][cH:19][c:20]([Br:22])[s:21]2)[O:16]1Participants
7
Sources & evidence
- ORD record
- ord-6f5e4b821d274662b3ad65d1b4fdbb76
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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