4'-(Bromomethyl)-2-cyanobiphenyl → Methyl 2-[N-(tert-Butoxycarbonyl)-N-[(2'-cyanobiphenyl-4-yl)methyl]amino]-3-nitrobenzoate
Reaction equation
[Br:17][CH2:18][C:19]1([CH2:20][Br:21])[CH:22]=[CH:23][C:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]2[C:31]#[N:32])=[CH:33][CH2:34]1.[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:11]#[N:12])[cH:13][cH:14][cH:15][cH:16]2)[cH:7][cH:8]1.[C:35]([CH3:36])([CH3:37])([CH3:38])[O:39][C:40](=[O:41])[NH:42][c:43]1[c:44]([C:45](=[O:46])[O:47][CH3:48])[cH:49][cH:50][cH:51][c:52]1[N+:53](=[O:54])[O-:55]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[c:10]([C:11]#[N:12])[cH:13][cH:14][cH:15][cH:16]2)[cH:7][cH:8]1)[N:42]([C:40]([O:39][C:35]([CH3:36])([CH3:37])[CH3:38])=[O:41])[c:43]1[c:44]([C:45](=[O:46])[O:47][CH3:48])[cH:49][cH:50][cH:51][c:52]1[N+:53](=[O:54])[O-:55]Participants
4
Sources & evidence
- ORD record
- ord-ba504f14a1b946f799a56187354ea6a4
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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