3-Chlorobenzo(b)thiophene-2-carbonyl chloride → tert-Butyl (4-{(3-chloro-benzo[b]thiophene-2-carbonyl)-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzyl]-amino}-cyclohexyl)-methyl-carbamate
Reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:5][NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])[CH2:11][CH2:12]2)[cH:22][c:23](-[c:26]2[cH:27][n:28][c:29]([CH3:32])[cH:30][cH:31]2)[cH:24][cH:25]1.[Cl:33][c:34]1[c:35]2[c:36]([s:37][c:38]1[C:39](=[O:40])[Cl:41])[cH:42][cH:43][cH:44][cH:45]2>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][N:6]([CH:7]2[CH2:8][CH2:9][CH:10]([N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])[CH2:11][CH2:12]2)[C:39]([c:38]2[c:34]([Cl:33])[c:35]3[c:36]([s:37]2)[cH:42][cH:43][cH:44][cH:45]3)=[O:40])[cH:22][c:23](-[c:26]2[cH:27][n:28][c:29]([CH3:32])[cH:30][cH:31]2)[cH:24][cH:25]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7728fbfa7db84722b56d6889d19c6ee3
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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