Water → 6-Bromo-5-piperidin-1-yl-pyrazine-2-carboxylic acid methyl ester
Reaction equation
[Br:17][Br:18].[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][cH:7][c:8]([N:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[n:9][cH:10]1.[Cl:19][CH2:20][Cl:21].[Cl:23][CH:24]([Cl:25])[Cl:26].[OH2:22]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6][c:7]([Br:17])[c:8]([N:11]2[CH2:12][CH2:13][CH2:14][CH2:15][CH2:16]2)[n:9][cH:10]1Participants
6
Sources & evidence
- ORD record
- ord-4b08940cf4c940a2baf7ad21ad9b8c1b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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