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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 949039Generated: October 26, 2026

Ethanol → 2-(1-{[5-(Cyclopropylmethoxy)-2-methylphenyl]carbonyl}piperidin-4-yl)-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

https://huagongshe.com/reaction/949039

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantBromomethylcyclopropaneHCID 81503—
Reactant5-(3,4-Dimethoxyphenyl)-2-{1-[(5-hydroxy-2-methylphenyl)carbonyl]piperidin-4-yl}-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-oneHCID 46202067—
Reactant5-(3,4-Dimethoxyphenyl)-2-{1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-yl}-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-oneHCID 46202396—
Product2-(1-{[5-(Cyclopropylmethoxy)-2-methylphenyl]carbonyl}piperidin-4-yl)-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-oneHCID 67365368—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fb872619f2a740d1a2de417b073322e8
Source noteValidation data from https://doi.org/10.1039/C8SC04228D