2-Iodothiazole → 5-Thiazol-2-yl-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([B:17]3[O:18][C:19]([CH3:20])([CH3:21])[C:22]([CH3:23])([CH3:24])[O:25]3)[cH:14][c:15]2[CH2:16]1.[I:26][c:27]1[s:28][cH:29][cH:30][n:31]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13](-[c:27]3[s:28][cH:29][cH:30][n:31]3)[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-8dafbfb601534f16b939b5d943de3a8d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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