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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 949301Generated: October 30, 2026

Hydrochloric Acid → Tert-butyl 4-(3,3-difluoropyrrolidin-1-YL)piperidine-1-carboxylate

https://huagongshe.com/reaction/949301

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantSodium ionHCID 923—
ReactantTetrahydrofuranHCID 8028—
ReactantCyano-borohydrideHCID 498716—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
Reactant3,3-DifluoropyrrolidineHCID 2782827—
ProductTert-butyl 4-(3,3-difluoropyrrolidin-1-YL)piperidine-1-carboxylateHCID 53419023—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-c341fd2c34254e9e87b93cf0cb7dfb65
Source noteValidation data from https://doi.org/10.1039/C8SC04228D