Methanol → Tert-butyl 2-[3-acetyl-4-[(3,5-difluorophenyl)methyl]-2,2-dimethyl-1,3-oxazolidin-5-yl]-4-hydroxypyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]2[CH:22]([CH2:31][c:32]3[cH:33][c:34]([F:39])[cH:35][c:36]([F:38])[cH:37]3)[N:23]([C:28]([CH3:29])=[O:30])[C:24]([CH3:26])([CH3:27])[O:25]2)[CH2:10][CH:11]([O:13][CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12]1.[CH3:42][OH:43].[H:40][H:41]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]2[CH:22]([CH2:31][c:32]3[cH:33][c:34]([F:39])[cH:35][c:36]([F:38])[cH:37]3)[N:23]([C:28]([CH3:29])=[O:30])[C:24]([CH3:26])([CH3:27])[O:25]2)[CH2:10][CH:11]([OH:13])[CH2:12]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-232fe558b99b4ce4af51ab618bb7031e
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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