3-(4-Bromophenyl)-6-fluoro-2,3-dihydro-1,4-benzodioxine → 1-[4-(7-Fluoro-2,3-dihydro-benzo[1,4]dioxin-2-yl)-benzyl]-pyrrolidine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:6]2[O:7][c:8]3[cH:9][c:10]([F:11])[cH:12][cH:13][c:14]3[O:15][CH2:16]2)[cH:17][cH:18]1.[F:19][c:20]1[cH:21][cH:22][c:23]2[c:24]([cH:42]1)[O:25][CH:26]([c:29]1[cH:30][cH:31][c:32]([CH2:33][N:34]3[CH2:35][CH2:36][O:37][CH2:38][CH2:39]3)[cH:40][cH:41]1)[CH2:27][O:28]2>>[F:19][c:20]1[cH:21][cH:22][c:23]2[c:24]([cH:42]1)[O:25][CH:26]([c:29]1[cH:30][cH:31][c:32]([CH2:33][N:34]3[CH2:35][CH2:36][CH2:38][CH2:39]3)[cH:40][cH:41]1)[CH2:27][O:28]2Participants
3
Sources & evidence
- ORD record
- ord-e26e05edcd434798bf20aa65e10f7958
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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