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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 949481Generated: October 29, 2026

Chloride → 9-Chloromethyl-1-(2-trimethylsilanylethoxymethyl)-1,3,4,5-tetrahydrobenz[b]azepin-2-one

https://huagongshe.com/reaction/949481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorideHCID 312—
ReactantPyridineHCID 1049—
ReactantDimethylformamideHCID 6228—
ReactantThionyl ChlorideHCID 24386—
ReactantLithium ionHCID 28486—
ReactantHCID 68499756HCID 68499756—
Product9-Chloromethyl-1-(2-trimethylsilanylethoxymethyl)-1,3,4,5-tetrahydrobenz[b]azepin-2-oneHCID 68502299—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-fd024c8f320b447ba20ce3526168e38e
Source noteValidation data from https://doi.org/10.1039/C8SC04228D