2-Methoxyphenylboronic acid → 5'-(2'-Methoxy-6-methyl-biphenyl-3-ylcarbamoyl)-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([c:12]2[n:13][cH:14][c:15]([C:18]([NH:19][c:20]3[cH:21][c:22]([I:27])[c:23]([CH3:26])[cH:24][cH:25]3)=[O:28])[cH:16][cH:17]2)[CH2:10][CH2:11]1.[CH2:40]([O:41][C:42]([CH:43]1[CH2:44][CH2:45][N:46]([c:47]2[cH:48][cH:49][c:50]([C:51](=[O:52])[NH:53][c:54]3[cH:55][cH:56][c:57](-[c:58]4[cH:59][cH:60][cH:61][cH:62][cH:63]4)[c:64]([CH3:65])[cH:66]3)[cH:67][n:68]2)[CH2:69][CH2:70]1)=[O:71])[CH3:72].[O:29]([CH3:30])[c:31]1[c:32]([B:37]([OH:38])[OH:39])[cH:33][cH:34][cH:35][cH:36]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([c:12]2[n:13][cH:14][c:15]([C:18]([NH:19][c:20]3[cH:21][c:22](-[c:32]4[c:31]([O:29][CH3:30])[cH:36][cH:35][cH:34][cH:33]4)[c:23]([CH3:26])[cH:24][cH:25]3)=[O:28])[cH:16][cH:17]2)[CH2:10][CH2:11]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-73782c4215aa4377911f8989c9884479
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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