2-(2,5-Dichloro-pyrimidin-4-ylamino)-N,N-dimethyl-benzenesulfonamide → 2-{5-Chloro-2-[8-methoxy-3-(2-morpholin-4-yl-2-oxo-ethyl)-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ylamino]-pyrimidin-4-ylamino}-N,N-dimethyl-benzenesulfonamide
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1.[NH2:22][c:23]1[cH:24][c:25]2[c:26]([cH:41][c:42]1[O:43][CH3:44])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1)[CH2:30][CH2:31]2>>[c:2]1([NH:22][c:23]2[cH:24][c:25]3[c:26]([cH:41][c:42]2[O:43][CH3:44])[CH2:27][CH2:28][N:29]([CH2:32][C:33](=[O:34])[N:35]2[CH2:36][CH2:37][O:38][CH2:39][CH2:40]2)[CH2:30][CH2:31]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[N:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-aa1fd82f2e7e4aa9b198ef698476a186
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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