Water → 2,6-dichloro-4-(chloromethyl)pyridine

HRID 949946Notes

Reaction equation

HRID 949946 reaction equation
[CH3:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[CH3:29][CH2:30][O:31][CH2:32][CH3:33].[Cl:1][c:2]1[n:3][c:4]([Cl:10])[cH:5][c:6]([CH2:8][OH:9])[cH:7]1.[OH2:21].[S:17]([Cl:18])([Cl:19])=[O:20].[cH:11]1[cH:12][cH:13][n:14][cH:15][cH:16]1>>[Cl:1][c:2]1[n:3][c:4]([Cl:10])[cH:5][c:6]([CH2:8][Cl:19])[cH:7]1

Participants

7

Reactant 6

HCID 962WaterHCID 1049PyridineHCID 1140TolueneHCID 3283Diethyl EtherHCID 24386Thionyl ChlorideHCID 2794840(2,6-Dichloropyridin-4-yl)methanol

Product 1

HCID 27946262,6-dichloro-4-(chloromethyl)pyridine

Sources & evidence

ORD record
ord-5c901fed25ce4ce0b737e207bccb86ae
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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