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HRID9501

反应详情

EQUATION

反应方程式

HRID 9501 的结构方程式

REACTANTS

反应物

2
结构：CCCCc1nc2c(N)nc3cc(Br)ccc3c2n1CCNS(C)(=O)=O
HCID21984323

未命名化合物

结构：C=C[B-](F)(F)F.[K+]
HCID23679353

Potassium ethenyl(trifluoro)borate(1-)

C2H3BF3K

PRODUCTS

生成物

1
结构：C=Cc1ccc2c(c1)nc(N)c1nc(CCCC)n(CCNS(C)(=O)=O)c12
HCID21984133

未命名化合物

PROCEDURE

实验过程

N-[2-(4-Amino-7-bromo-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide was coupled with potassium vinyltrifluoroborate according to the procedure described in Part D of Examples 440–455 and recrystallized from acetonitrile to provide N-[2-(4-amino-2-butyl-7-vinyl-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]methanesulfonamide as an off-white solid.

WORKUP

后处理

  1. customrecrystallized from acetonitrile