HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 950118Generated: October 30, 2026
Hydrochloric Acid → 4-(1-(5-Chloropyrimidin-2-yl)piperidin-4-yloxy)-1-(4-(methylsulfonyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile
https://huagongshe.com/reaction/950118
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-Chloro-2-iodopyrimidine | HCID 29938005 | — |
| Reactant | 1-(4-Methylsulfonylphenyl)-6-oxo-4-piperidin-4-yloxypyridazine-3-carbonitrile | HCID 67444877 | — |
| Product | 4-(1-(5-Chloropyrimidin-2-yl)piperidin-4-yloxy)-1-(4-(methylsulfonyl)phenyl)-6-oxo-1,6-dihydropyridazine-3-carbonitrile | HCID 44621143 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
|---|
| ORD ID | ord-803ce14fc3c04655baec84b722e75fee |
|---|
| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
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