(1-methyl-1H-pyrazol-4-yl)methanamine → 4-methyl-N-((1-methyl-1H-pyrazol-4-yl)methyl)-2-(2-oxo-3-(4,4,4-trifluorobutyl)imidazolidin-1-yl)thiazole-5-carboxamide
Reaction equation
[CH3:10][n:11]1[n:12][cH:13][c:14]([CH2:16][NH2:17])[cH:15]1.[CH3:18][c:19]1[n:20][c:21]([N:27]2[C:28](=[O:39])[N:29]([CH2:32][CH2:33][CH2:34][C:35]([F:36])([F:37])[F:38])[CH2:30][CH2:31]2)[s:22][c:23]1[C:24](=[O:25])[OH:26].[F:1][c:2]1[cH:3][c:4]([CH2:5][NH2:6])[cH:7][n:8][cH:9]1>>[CH3:10][n:11]1[n:12][cH:13][c:14]([CH2:16][NH:17][C:24]([c:23]2[c:19]([CH3:18])[n:20][c:21]([N:27]3[C:28](=[O:39])[N:29]([CH2:32][CH2:33][CH2:34][C:35]([F:36])([F:37])[F:38])[CH2:30][CH2:31]3)[s:22]2)=[O:25])[cH:15]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-108501770da34de28f1c4d32d8bfa46c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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